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Last publication Press

Carthera signs strategic collaboration with Accord Healthcare

November 6, 2023 - Carthera announces the signing of a strategic collaboration with Accord Healthcare Limited, a leading pharmaceutical company, for the supply of carboplatin.

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Press

Carthera appoints Dr. Oern Stuge as chairman of board of directors

September 18, 2023 – Medical device industry executive with 30+ years expertise brings wealth of experience in product development and commercial launches to support Carthera’s future growth.

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Press

Carthera closes €37.5M Series B funding round

June 27, 2023 - New funds will help launch pivotal multicenter trial in patients with recurrent glioblastoma and advance clinical pipeline.

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Press

Promising results from SonoCloud-9 clinical trial in combination with nab-paclitaxel have been published in Lancet Oncology

May 3, 2023 - Four-to six-fold increase in drug concentrations measured in human brain after blood-brain barrier opening with SonoCloud-9 System

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Press

Carthera announces positive outcome of End-of-Phase 2 meeting with FDA for SonoCloud-9 system for treatment of recurrent glioblastoma

March 13, 2023 - Carthera and FDA aligned on key aspects of proposed pivotal trial design.

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Press

Carthera receives FDA Breakthrough Device Designation for SonoCloud-9 system

June 22, 2022 - Breakthrough Status allows for enhanced interaction with FDA and recognizes SonoCloud® as innovative and promising approach for treatment of recurrent glioblastoma.

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Press

SonoCloud® technology enhances the efficacy of immunotherapies for the treatment of brain tumor.

June 9, 2021 - SonoCloud® device can enhance delivery of CAR-T therapies and penetration of checkpoint inhibitors into the brain of preclinical glioma models.

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Press

Launch of a new phase I/IIclinical trial in collaboration with Northwestern University in Chicago

December 16, 2020 - The trial will recruit up to 39 patients with recurrent glioblastoma to test the SonoCloud-9 device in combination with Abraxane®.

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Press

Carthera receive €2M grant and €10.5M equity from the European Innovation Council

September 14, 2020 - Carthera announces that it has been selected by the EIC (European Innovation Council) pilot gas pedal program for the development of its DOMEUS project.

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Press

First patient enrolled in new clinical trial for SonoCloud technology in melanoma

June 8, 2020 - The SoniMel study aims to demonstrate safety of using the SonoCloud® technology with checkpoint inhibitors for the treatment of brain metastases from melanoma.

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    logo-carthera Scientific Publications

    Last publication Scientific publication

    Repeated blood–brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial

    Lancet Oncology - May 2023

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    Scientific publication

    Evaluating drug delivery enhancement following ultrasound treatment

    Lancet Oncology - May 2023

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    Scientific publication

    Advances in Blood-Brain Barrier Disruption to Facilitate Drug Delivery for Infiltrative Gliomas

    Advances in Oncology - May 2023

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    Scientific publication

    Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials

    Cancers - January 2023

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    Scientific publication

    Low-Intensity Pulsed Ultrasound-Mediated Blood-Brain Barrier Opening Increases Anti-Programmed Death-Ligand 1 Delivery and Efficacy in Gl261 Mouse Model

    Pharmaceutics - January 2023

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    Scientific publication

    Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer's disease

    Alzheimer’s Research & Therapy - March 2022

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    Scientific publication

    Opening of the Blood-Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models

    Clinical Cancer Research - August 2021

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    Scientific publication

    Ultrasound-induced blood-brain barrier disruption for the treatment of gliomas and other primary CNS tumors

    Cancer Letters - June 2020

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    Scientific publication

    Blood–brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors

    Journal of Neuro-Oncology - February 2020

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    Scientific publication

    Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations

    Clinical Cancer Research - January 2020

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