SonoProbe®

High Intensity Contact Ultrasound Interstitial Medical Device

The Sonoprobe Medical Device

SonoProbe is a diagnostic and therapeutic treatment probe percutaneously introduced in a tumor under local anaesthesia. Slightly larger than a biospy needle, the SonoProbe is composed of dozens of miniaturized ultrasound transducers that are able to emit high intensity ultrasound waves for therapy.

Treatments with the SonoProbe are continuously monitored and controlled by software that interfaces with an MR imaging system, performs treatment simulations, and executes treatments with real-time temperature feedback control.

In the figure below, the color code corresponds to heating of brain tissue around the probe. On this figure, the probe is artificially represented for clarity, as the probe is nearly invisible on the MR images.

This innovation and development are currently in pre-clinical testing, which will soon allow for an application in humans for the treatment of brain tumors.  

 

 

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  • News CarThera

    14.10.2016
    CarThera secures €5.7 million in funding for its DOME project

    October 12, 2016 – CarThera has received a grant of €5.7 million ($6.4m) for its DOME project. The funding was awarded under the call for proposals ‘Structuring R&D Projects for Competitiveness’ from France’s ‘Investments for the Future Program’, led by the General Investment Commission and run by Bpifrance.

    The grant will finance our SonoCloud Phase 2b/3 study in glioblastoma that will involve around 200 patients at centers in Europe and the United States. It will also fund a number of exploratory studies, including one on Alzheimer’s disease, building on the findings from the Phase 1/2a study that paved the way for a broader array of clinical indications.

    15.06.2016
    A world first published in Science Translational Medicine

    SonoCloud® uses ultrasound to achieve permeability of blood vessels in human brain, allowing increased penetration of therapeutic molecules

    Scientific paper published on June 15th 2016 in Science Translational Medicine supports concept of intracranial ultrasound implant developed by CarThera
     
    Research teams from AP-HP hospitals, UPMC University, INSERM laboratories and the ICM incubator performed this breakthrough on brain tumors, paving the way for broader applications in neurological disorders

    27.04.2016
    The Biovision 2016 Investor Conference selection committee special award went to CarThera!

    The Investor Conference of Biovision is a unique opportunity for selected startups (28 over 120 candidates) to pitch in front of a jury of 15 of the major European VC.

    Biovision, The World Life Sciences Forum, brings together international decision makers from the academic, private, policy-making and civil society sectors. It took place 13–14 April 2016 in Lyon, France.