Carthera®

“Advanced Brain Therapies Through Innovation” 

CarThera® designs and develops innovative medical devices using the therapeutic potential of ultrasound to significantly improve the efficacy, comfort, and cost of treating a range of medical conditions.

CarThera® has focused on the treatment of brain tumors for the first applications of its innovative medical devices. CarThera’s devices are developed by a multidisciplinary team of medical doctors, biologists, and physicists. This multidisciplinary effort takes into account, from the early stages of development, the needs of both patients and physicians, and leads to innovative solutions.

The medical devices developed by CarThera originate from the work of Dr. Alexandre Carpentier, a neurosurgeon at the University Hospital Pitié-Salpêtrière in Paris, France. They are designed to respond to unmet clinical needs.

 

The two medical devices currently in development are designed to be used during outpatient procedures for the thermal ablation of brain tumors (SonoProbe) and for improving the efficacy of chemotherapy (SonoCloud®).

Both devices are innovative at multiple levels: 

Biologically — They employ the use of new tissue-ultrasound interactions. 

Clinically — They use interventional MRI procedures for the brain. 

Technologically — They use advanced technology for miniaturization. 

Organizationally — They open the possibility of new methods of outpatient care.

 

 

photo_carpentier

Pr Carpentier Interview  / Autrement Editions – may 2011.

 

 

 

« A new vision of surgery »

“I have always been interested in the development of new surgical technologies. Even though current surgical techniques provide an immense benefit to patients, I’m convinced that we can do even better, with the development of techniques that decrease both invasiveness and expense.  My medical objective is a bit idealistic: I envision surgery as a convergence of medical expertise, advanced materials, physical principles, and computational power. Such a convergence will allow for treatments with better efficacy and security, with diminished morbidity, under local anaesthesia, and on an outpatient basis. It may appear unfeasible, but we are on the way to success: We now have proof of concept and efficacy in pre-clinical studies for our two technologies under development.”

 

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  • News CarThera

    13.12.2018
    CarThera closes €9M ($10.3M) Series B funding round

    €9M ($10.3M) was raised with three institutional investors, Panakès Partners, Sham Innovation Santé (advised by Turenne Capital) and Supernova Invest via its fund Supernova 2, as well as Group Arnault and historical investors. The proceeds will be used to further advance the SonoCloud technology and develop the clinical pipeline of the company. A multi-center study has already been launched in France and in the US to evaluate the SonoCloud-9 device, a new generation of implant with nine ultrasound emitters, in patients with recurrent glioblastoma. The company also has an on-going clinical study with the SonoCloud-1 device in patients with Alzheimer’s disease and one planned for patients with brain metastases.

    09.06.2018
    ASCO 2018: CarThera presents promising preliminary efficacy data for treating recurrent glioblastoma

    Preliminary data from the first clinical trial of the company’s intracranial ultrasound implant, SonoCloud®, show a good safety profile and promising trends in overall survival.

    Dr. Ahmed Idbaih, AP-HP principal investigator of the Phase 1/2a clinical trial (NCT02253212) presented a preliminary analysis of the data from 21 glioblastoma patients who received 65 SonoCloud® treatments. Overall Survival was increased from 8.5 to 12.9 months in patients who had SonoCloud®-induced BBB opening.

    18.05.2018
    May 2018 – CarThera will participate to BIO 2018 in Boston

    CarThera will participate to the BIO International Convention in Boston on June 4-7 to meet with global biotech and pharma leaders and showcase its SonoCloud device.

    Should you want to meet us at BIO and hear more about SonoCloud – our ultrasound device, aimed at improving treatment efficiency by temporarily opening the Blood Brain Barrier – contact us at contact@carthera.eu and come to Booth 527 at the France Pavilion.